His first client in Missoula is Johnny American Horse, a young activist for land preservation and the rights of Native Americans. Johnny is charged with the murder of two mysterious men -- who seem to have recently tried to kill Johnny themselves, or at least scare him off his political causes. As Billy Bob investigates, he discovers a web of intrigue surrounding the case and its players: Johnny's girlfriend, Amber Finley, as reckless as she is defiant -- and the daughter of one of Montana's U.S. senators; Darrel McComb, a Missoula police detective who is obsessed with Amber; and Seth Masterson, an enigmatic government agent whose presence in town makes Billy Bob wonder why Washington has become so concerned with an obscure murder case on the fringes of the Bitterroot Mountains.

As complications mount and the dead bodies multiply, Billy Bob is drawn closer to the truth behind Johnny American Horse's arrest -- and discovers a greater danger to himself and to his whole family. How Billy Bob strikes back at evil and protects his kin is the masterful triumph of In the Moon of Red Ponies.